Cannabis directly interacts with the brain and central nervous system. THC generally produces an intoxicating or impairing effect, even when very little is consumed. In moderate consumption, effects may include a sense of relaxation and pleasant euphoria. THC can also cause unpleasant or harmful effects. Senses may be heightened. The effects vary from person to person and will further depend on strain, consumption method and personal factors like genetics, existing mental health conditions, current mood, age, personality and gender.